Studies on the synthesis of tedanolide: Synthesis of the C(5)-C(21) segment via a highly stereoselective fragment assembly aldol reaction of a chiralbeta,gamma-unsaturated methyl ketone

Authors
Roush, WR Lane, GC
Citation
Wr. Roush et Gc. Lane, Studies on the synthesis of tedanolide: Synthesis of the C(5)-C(21) segment via a highly stereoselective fragment assembly aldol reaction of a chiralbeta,gamma-unsaturated methyl ketone, ORG LETT, 1(1), 1999, pp. 95-98
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
1
Issue
1
Year of publication
1999
Pages
95 - 98
Database
ISI
SICI code
1523-7060(19990715)1:1<95:SOTSOT>2.0.ZU;2-D
Abstract
[GRAPHICS] A highly diastereoselective synthesis of 3, corresponding to the C(5)-C(21) segment of tedanolide, has been accomplished by a route utilizing the aldo l reaction of aldehyde 4 and the beta,gamma-unsaturated methyl ketone 5.