Nuclear magnetic resonance monitoring of treatment and prediction of outcome in multiple sclerosis

Magnetic resonance (MR) techniques provide an objective, sensitive and quan titative assessment of the evolving pathology in multiple sclerosis. There is an increasing definition of the pathological specificity of newer techni ques, and more robust correlations with clinical evolution are emerging. As the pathophysiological basis of in vivo nuclear MR signal abnormalities is further elucidated, it is likely that the importance of MR as a tool to mo nitor new therapies will increase.