Wem. Prysephillips et al., GUIDELINES FOR THE DIAGNOSIS AND MANAGEMENT OF MIGRAINE IN CLINICAL-PRACTICE, CMAJ. Canadian Medical Association journal, 156(9), 1997, pp. 1273-1287
Objective: To provide physicians and allied health care professionals
with guidelines for the diagnosis and management of migraine in clinic
al practice. Options: The full range and quality of diagnostic and the
rapeutic methods available for the management of migraine. Outcomes: I
mprovement in the diagnosis and treatment of migraine, which will lead
to a reduction in suffering, increased productivity and decreased eco
nomic burden. Evidence and values: The creation of the guidelines foll
owed a needs assessment by members of the Canadian Headache Society an
d included a statement of objectives; development of guidelines by mul
tidisciplinary working groups using information from literature review
s and other resources; comparison of alternative clinical pathways and
description of how published data were analysed; definition of the le
vel of evidence for data in each case; evaluation and revision of the
guidelines at a consensus conference held in Ottawa on Oct. 27-29, 199
5; redrafting and insertion of tables showing key variables and data f
rom various studies and tables of data with recommendations; and reass
essment by all conference participants. Benefits, harms and costs: Acc
uracy in diagnosis is a major factor in improving therapeutic effectiv
eness; Improvement in the precise diagnosis of migraine, coupled with
a rational plan for the treatment of acute attacks and for prophylacti
c therapy, is likely to lead to substantial benefits in both human and
economic terms. Recommendations: The diagnosis of migraine can be imp
roved by using modified criteria of the International Headache Society
as well as a semistructured patient interview technique. Appropriate
treatment of symptoms should take into account the severity of the mig
raine attack, since most patients will have attacks of differing sever
ity and can learn to use medication appropriate for each attack. When
headaches are frequent or particularly severe, prophylactic therapy sh
ould be considered. Both the avoidance of migraine trigger factors and
the application of nonpharmacological therapies play important roles
in overall migraine management and will be addressed at a later date.
Validation: The guidelines are based on consensus of Canadian experts
in neurology, emergency medicine, psychiatry, psychology, family medic
ine and pharmacology, and consumers. Previous guidelines did not exist
. Field testing of the guidelines is in progress. Sponsors: Support fo
r the consensus conference was provided by an unrestricted educational
grant from Glare Wellcome Inc. Editorial coordination was provided by
Medical Education Programs Canada Inc.