Is the identification of antibodies against the nervous tissue an indicator of brain injury?

Citation
I. Stankova et al., Is the identification of antibodies against the nervous tissue an indicator of brain injury?, PHYSL RES, 48(5), 1999, pp. 383-387
Citations number
7
Categorie Soggetti
Physiology
Journal title
PHYSIOLOGICAL RESEARCH
ISSN journal
08628408 → ACNP
Volume
48
Issue
5
Year of publication
1999
Pages
383 - 387
Database
ISI
SICI code
0862-8408(1999)48:5<383:ITIOAA>2.0.ZU;2-9
Abstract
Using a modification of the ELISA method, auto-antibodies against the own n ervous tissue have been identified in the serum of laboratory rats. The pre valence of the IgM class of antibodies suggests their physiological signifi cance. Antibody levels are higher in females than in males. Brain hypoxic i njury brings about a shift in the spectrum of antibodies rewards the IgG cl ass. It I nay thus serve as an indicator of brain impairment caused by a la ck of oxygen.