A study was undertaken regarding the prevalence of bovine viral diarrhoea v
irus (BVDV) antibodies in bovine sera which tested negative for rinderpest
and peste des petits ruminants virus antibodies. The samples were collected
between January 1996 and December 1997. A total of 439 samples (327 cattle
and 112 buffalo from 17 states of India) were tested using a commercial en
zyme-linked immunosorbent assay (ELISA) kit. The mean prevalence of BVDV an
tibodies in cattle was 15.29% (50/327) in 16 states compared to 23.21% (26/
112) in buffalo in 9 states, with an overall prevalence of 17.31% (76/439)
in 17 states. The serological evidence that BVDV infection is widespread in
India is of utmost practical importance because of the clinical resemblanc
e to rinderpest. A differential diagnosis between these two diseases is cri
tical in view of the declaration by India of provisional freedom from rinde
rpest disease; active sere-surveillance is to begin in 2000 to achieve cert
ification of freedom from rinderpest infection by the Office International
des Epizooties.