H. Nakashima et al., Polymorphisms within the interleukin-10 receptor cDNA gene (IL10R) in Japanese patients with systemic lupus erythematosus, RHEUMATOLOG, 38(11), 1999, pp. 1142-1144
Objective. To assess the association between polymorphisms within the inter
leukin-10 receptor cDNA gene (IL10R) and systemic erythematosus (SLE) in Ja
panese people.
Method. We examined the IL-10 receptor genotype of 109 SLE patients and 102
healthy subjects by the reverse transcription-polymerase chain reaction-re
striction fragment length polymorphism (RT-PCR-RFLP) method.
Results. There was no difference in the IL10R genotype frequencies of these
two groups.
Conclusion. The IL10R genotype does not determine susceptibility to SLE in
Japanese people.