Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1

Citation
O. White et al., Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1, SCIENCE, 286(5444), 1999, pp. 1571-1577
Citations number
41
Categorie Soggetti
Multidisciplinary,Multidisciplinary,Multidisciplinary
Journal title
SCIENCE
ISSN journal
00368075 → ACNP
Volume
286
Issue
5444
Year of publication
1999
Pages
1571 - 1577
Database
ISI
SICI code
0036-8075(19991119)286:5444<1571:GSOTRB>2.0.ZU;2-Y
Abstract
The complete genome sequence of the radiation-resistant bacterium Deinococc us radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 bas e pairs), a megaplasmid (172,466 base pairs), and a small plasmid (45,704 b ase pairs), yielding a total genome of 3,284,156 base pairs. Multiple compo nents distributed on the chromosomes and megaplasmid that contribute to the ability of D. radiodurans to survive under conditions of starvation, oxida tive stress, and high amounts of DNA damage were identified. Deinococcus ra diodurans represents an organism in which all systems for DNA repair, DNA d amage export, desiccation and starvation recovery, and genetic redundancy a re present in one cell.