Diastereoselective allylation and alkylation of optically active imines with metallic samarium and a catalytic amount of iodine

Authors
Yanada, R Negoro, N Okaniwa, M Ibuka, T
Citation
R. Yanada et al., Diastereoselective allylation and alkylation of optically active imines with metallic samarium and a catalytic amount of iodine, TETRAHEDRON, 55(49), 1999, pp. 13947-13956
Citations number
41
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
49
Year of publication
1999
Pages
13947 - 13956
Database
ISI
SICI code
0040-4020(199912)55:49<13947:DAAAOO>2.0.ZU;2-W
Abstract
Barbier-type allylation and alkylation of optically active imines such as N -benzylidenevalinol methyl ether was performed with metallic samarium, a ca talytic amount of iodine, and allyl or alkyl halides. This reaction proceed ed in a highly diastereoselective manner in THF at room temperature. (C) 19 99 Elsevier Science Ltd. All rights reserved.