There is no consensus on optimal surgical treatment of unilateral aortoilia
c occlusive disease. The purpose of this study was to compare indications f
or and results of the various options. Patients undergoing primary, unilate
ral inflow procedures without adjunctive infrainguinal bypass over a 10-yea
r period were analyzed. Groups were defined as AxF for unilateral axillofem
oral bypass (18); IF for aortounifemoral (two) or ipsilateral iliofemoral (
29) bypass; and CF for contralateral iliac-to-femoral (six) or femorofemora
l (10) bypass. Risk factors, level and severity of occlusive disease, morbi
dity, mortality, cumulative primary patency, and limb salvage were compared
. Median age was 72 years, limb salvage was the surgical indication in 61%
of patients. Infrainguinal occlusion was present in 76.6% of the whole grou
p, while 27.7% had prior outflow procedures. Compared with the other groups
, AxF patients were older with more comorbidity and had more contralateral
iliofemoral occlusive disease (88.9% vs 48.4%, p < 0.01). IF patients more
frequently had prior outflow operations (48.4% vs 11.1%, p < 0.01). Comorbi
dity and presence of contralateral iliac disease most strongly influenced o
peration choice. Overall, hospital mortality rate was 3.1% and morbidity ra
te was 21.5%, not significantly different between groups. Early occlusion o
ccurred in three patients, two IF and one AxF. Life-table primary patency r
ate was 87.8% (SE +/- 4.9%) at 2 years and was not significantly different
among the groups. Three patients ultimately required contralateral inflow p
rocedures, 2 AxF, 1 IF (p = NS). Unilateral inflow operations achieve reaso
nable patency and good limb salvage rates. Shorter length reconstructions w
ere utilized preferentially when contralateral disease was not severe, but
despite greater age, comorbidity, and occlusive disease, axillounifemoral b
ypass results were not inferior to more direct reconstructions.