Autoimmune enteropathy is an increasingly recognized cause of severe protra
cted diarrhea, usually affecting infants and children predisposed to autoim
mune phenomena. Although this may be a common cause of diarrheal illness, i
t is scarcely recognized in the American literature. In association with th
ymoma, a case of so-called graft-vs-host-like colitis and 2 cases of chroni
c diarrhea associated with thymoma were reported but, to our knowledge, no
cases of autoimmune enteropathy have been reported as suck We describe 2 ad
ults with autoimmune enteropathy found in association with a thymoma.