Conjugate pneumococcal vaccines may soon allow immunization of healthy infa
nts against Streptococcus pneumoniae infection and protection against relat
ed episodes of meningitis, pneumonia, bacteremia, and otitis media. To meas
ure the potential economic impact of such an infant vaccination, a team of
investigators estimated the costs of specific pneumococcal dis-eases. Assum
ptions were based on health plan databases, surveys of parents, and publish
ed data. On the basis of preliminary analysis, the researchers estimated th
at the overall annual savings to society would be $763 million, and the sav
ings for health plans would be $307 million. These estimated savings will n
eed to be balanced against per-dose vaccination costs, which are unknown.