THE ASYMMETRIC MICHAEL REACTION INVOLVING CHIRAL IMINES - USE OF ACRYLONITRILE AS ACCEPTOR AND SUBSEQUENT FUNCTIONALIZATION OF THE ADDUCTS

Authors
DESMAELE D ZOUHIRI F DANGELO J
Citation
D. Desmaele et al., THE ASYMMETRIC MICHAEL REACTION INVOLVING CHIRAL IMINES - USE OF ACRYLONITRILE AS ACCEPTOR AND SUBSEQUENT FUNCTIONALIZATION OF THE ADDUCTS, Tetrahedron : asymmetry, 5(9), 1994, pp. 1645-1648
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
9
Year of publication
1994
Pages
1645 - 1648
Database
ISI
SICI code
0957-4166(1994)5:9<1645:TAMRIC>2.0.ZU;2-8
Abstract
Condensation of chiral imines 1 and acrylonitrile led to adduct (R)-6 with an ee greater than or equal to 95 %. This adduct has then been co nverted into chiral synthons 9, 11, 12 and 17.