Background: Upper and lower airways are similar in many ways, including com
mon triggers, pathogenic mechanisms, and response: to treatment. Explanatio
ns for the posed linkage between upper and lower airways include nasal-bron
chial reflux, postnasal drainage of inflammatory material into the lower ai
rways, and dry air impinging on the nasal mucoas.
Conclusion: Treatment modalities such as antihistamines and corticosteroid
aerosols by the nasal route improve both the upper and lower airways.