Ciguatera (poisoning caused by eating fish contaminated with algal tox
ins) is usually diagnosed clinically. We describe a Queensland family
of four (including a pregnant woman) with ciguatera, confirmed by bioa
ssay of the implicated fish for ciguatoxin. All four recovered, illust
rating the effectiveness of treatment with intravenous mannitol. At bi
rth, the infant appeared to suffer no adverse effects attributable to
ciguatera; to our knowledge, this is the first report of the effect of
severe ciguatera in the first trimester of pregnancy.