SYNTHESIS OF A HOMOCHIRAL ALPHA,ALPHA-DISUBSTITUTED ALPHA,BETA-DIAMINO-ACID

Authors
JONES RCF CROCKETT AK REES DC GILBERT IH
Citation
Rcf. Jones et al., SYNTHESIS OF A HOMOCHIRAL ALPHA,ALPHA-DISUBSTITUTED ALPHA,BETA-DIAMINO-ACID, Tetrahedron : asymmetry, 5(9), 1994, pp. 1661-1664
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
9
Year of publication
1994
Pages
1661 - 1664
Database
ISI
SICI code
0957-4166(1994)5:9<1661:SOAHAA>2.0.ZU;2-L
Abstract
The synthesis of a homochiral alpha,alpha-disubstituted alpha,beta-dia mino-acid is described from norleucine using stereospecific alkylation of a homochiral oxazolidinone enolate; an optically active pseudotetr apeptide analogue of CCK-4 is prepared to show an application of such diamino-acids.