SYNTHESIS OF HOMOCHIRAL ALPHA-AMINO-ACIDS BY REDUCTIVE AMINATION OF ALPHA-KETOACIDS VIA 3-SUBSTITUTED-5-PHENYL-3,4-DEHYDROMORPHOLIN-2-ONES - SYNTHESIS OF (S)-2-AMINOBUTANOIC AND (R)-2-AMINOBUTANOIC ACID

Authors
COX GG HARWOOD LM
Citation
Gg. Cox et Lm. Harwood, SYNTHESIS OF HOMOCHIRAL ALPHA-AMINO-ACIDS BY REDUCTIVE AMINATION OF ALPHA-KETOACIDS VIA 3-SUBSTITUTED-5-PHENYL-3,4-DEHYDROMORPHOLIN-2-ONES - SYNTHESIS OF (S)-2-AMINOBUTANOIC AND (R)-2-AMINOBUTANOIC ACID, Tetrahedron : asymmetry, 5(9), 1994, pp. 1669-1672
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
9
Year of publication
1994
Pages
1669 - 1672
Database
ISI
SICI code
0957-4166(1994)5:9<1669:SOHABR>2.0.ZU;2-C
Abstract
2-Oxobutanoic acid has been converted to (R)-or (S)-2-aminobutanoic ac id via highly diastereocontrolled hydrogenation of the corresponding h omochiral 3-ethyl-5-phenyl-3,4-dehydromorpholin-2-one derivatives.