Correlation between the consumption of amino acids and the production of the antibiotic gallidermin by Staphylococcus gallinarum

Authors
Kempf, M Theobald, U Fiedler, HP
Citation
M. Kempf et al., Correlation between the consumption of amino acids and the production of the antibiotic gallidermin by Staphylococcus gallinarum, BIOTECH LET, 21(11), 1999, pp. 959-963
Citations number
7
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
BIOTECHNOLOGY LETTERS
ISSN journal
01415492 → ACNP
Volume
21
Issue
11
Year of publication
1999
Pages
959 - 963
Database
ISI
SICI code
0141-5492(199911)21:11<959:CBTCOA>2.0.ZU;2-K
Abstract
The correlation between the consumption of amino acids and the production o f the polypeptide antibiotic gallidermin by Staphylococcus gallinarum Tu 39 28 was investigated by on-line determination of amino acids and pulse exper iments. A prolonged production phase together with an increase in galliderm in formation of about 25% was obtained during pulse and fed-batch experimen ts with the amino acids glutamic acid, glycine, serine and threonine.