A PRACTICAL SYNTHESIS OF THE ENANTIOMERS OF HYDROXYCHLOROQUINE

Authors
BLANEY PM BYARD SJ CARR G ELLAMES GJ HERBERT JM PEACE JE SMITH DI MICHNE WF SANNER MS
Citation
Pm. Blaney et al., A PRACTICAL SYNTHESIS OF THE ENANTIOMERS OF HYDROXYCHLOROQUINE, Tetrahedron : asymmetry, 5(9), 1994, pp. 1815-1822
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
9
Year of publication
1994
Pages
1815 - 1822
Database
ISI
SICI code
0957-4166(1994)5:9<1815:APSOTE>2.0.ZU;2-C
Abstract
An efficient synthesis of the enantiomeric forms of hydroxychloroquine is described. The method is suitable for the production of multigram quantities of the dihydrogenphosphate salts (R)-1b and (S)-1b.