DIASTEREOSPECIFIC CYCLIZATION OF OPTICALLY-ACTIVE TRIFLUOROMETHYLATEDEPOXYCARBAMATES

Authors
YAMAZAKI T IWATSUBO H KITAZUME T
Citation
T. Yamazaki et al., DIASTEREOSPECIFIC CYCLIZATION OF OPTICALLY-ACTIVE TRIFLUOROMETHYLATEDEPOXYCARBAMATES, Tetrahedron : asymmetry, 5(9), 1994, pp. 1823-1830
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
9
Year of publication
1994
Pages
1823 - 1830
Database
ISI
SICI code
0957-4166(1994)5:9<1823:DCOOT>2.0.ZU;2-9
Abstract
Optically active trifluoromethylated propargylic alcohol was prepared by enzymatic asymmetric hydrolysis and was transformed into chiral ami noalcohol derivatives in a diastereospecific fashion, whose results we re qualitatively supported by semiempirical molecular orbital calculat ions.