Analysis of Minnesota Multiphasic Personality Inventory-2 profiles of prospective anonymous oocyte donors in relation to the outcome of the donor selection process

Objective: To examine the scores of prospective anonymous oocyte donors on the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) in four outcome groups. Design: Chart review. Setting: Academic medical center. Patient(s): One hundred fifty prospective anonymous oocyte donors who under went a preliminary screening and a 1-hour structured psychological intervie w and who completed the MMPI-2. Intervention(s): Psychological evaluation prior to donation. Main Outcome Measure(s): Scores on the MMPI-2 and outcomes of the donor sel ection process. Result(s): Seventy (47%) women were accepted as donors and completed one do nation cycle; 30 (20%) were accepted as donors but did not donate because o f medical reasons or relocation; 18 (12%) were accepted as donors but were noncompliant; and 32 (21%)were rejected as donors because of psychological concerns. Statistically significant differences were found between outcome groups on scales F, K, 1, 2, 7, 8, and 0. Although these differences were s tatistically significant, all group subscale mean scores were in the averag e to low-average range and differences between group means were small. Conclusion(s): The MMPI-2 differentiates between prospective donor outcome groups, but psychologists need to interpret the results of the MMPI-2 caref ully in the context of clinical interview information. (C) 1999 by American Society for Reproductive Medicine.