Description of the Genetic Analysis Workshop 11 Collaborative Study on theGenetics of Alcoholism

Problem I of Genetic Analysis Workshop 11 consists of data from a family st udy of the genetics of alcoholism and related traits contributed by the six centers making up the National Institute for Alcohol Abuse and Alcoholism sponsored by the Collaborative Study on the Genetics of Alcoholism (COGA). The family data included 1,214 members of 105 pedigrees ascertained for hav ing three or more individuals affected with alcoholism. Data available to w orkshop participants included clinical phenotypes, personality measures, sm oking behavior, event-related potentials, platelet monamine oxidase B activ ity, and a genome scan of 296 markers. (C) 1999 Wiley-Liss, Inc.