Synthesis of some new imidazo[1,2-c]pyrimido[4 ',5 ': 6,5]pyrano[3,2-h]quinoline derivatives

5-Dimethylaminosulfonyl-8-quinolinol (1) was reacted with cinnamonitriles ( 2a,b) to give the corresponding pyranoquinolines (3a,b). Reaction of 3a,b w ith ethylenediamine yielded 2-amino-4-aryl-3-(4,5-dihydro-1H-imidazo- 2-yl) pyrano[3,2-h]quinolines (4a,b). Compounds (4a,b) were reacted with triethyl orthoformate, aldehyde, ketone and carbon disulfide to give the correspond ing imidazo[1,2-c]pyrimido[4',5': 6,5]pyrano[3,2-h]quinoline derivatives (5 a,b-15a,b).