Citation
M. Cugno et al., Cardiopulmonary bypass increases plasma bradykinin concentrations, IMMUNOPHARM, 43(2-3), 1999, pp. 145-147
Citations number
5
Categorie Soggetti
Immunology
Journal title
IMMUNOPHARMACOLOGY
ISSN journal
01623109
→ ACNP
Volume
43
Issue
2-3
Year of publication
1999
Pages
145 - 147
Database
ISI
SICI code
0162-3109(199909)43:2-3<145:CBIPBC>2.0.ZU;2-G
Abstract
An increase of bradykinin (BK) plasma levels together with the activation c
oagulation cascade, fibrinolysis, complement and cytokines was observed dur
ing cardiopulmonary bypass (CPB). Since the procedure of extracorporeal cir
culation completely excludes the lung, the major site of BK catabolism, our
data suggest that a reduced catabolism could contribute to the increase of
BK during CPB. (C) 1999 Published by Elsevier Science B.V. All rights rese
rved.