Orbital magnetic resonance imaging demonstrated increased signal of the opt
ic nerve in short time inversion recovery (STIR) images of two young women
with unilateral visual blurring. In both, recurrent oral and genital ulcera
tions and papulopustular lesions appeared within the next 14-15 months, res
pectively, allowing a diagnosis of Behcet's disease. Optic neuropathy may b
e an early manifestation of Behcet's disease and clinical follow-up is cruc
ial for its diagnosis.