P. Magnani et al., FDG/PET and spiral CT image fusion for medistinal lymph node assessment ofnon-small cell lung cancer patients, J CARD SURG, 40(5), 1999, pp. 741-748
Background. To assess the potential usefulness of F-18-FDG/PET and spiral-C
T images concurrent assessment and coregistration in staging mediastinal ly
mph node involvement in patients with non small cell lung cancer.
Methods, 28 patients waiting to undergo surgical treatment underwent spiral
-CT and PET examinations on the same day. The results of the two studies we
re interpreted separately, together (CT&PET) and following their fusion in
a single image (CT+PET). Results of spiral-CT, PET, CT&PET and CT+PET were
assessed with respect to the histological diagnosis.
Results, A correct assessment of mediastinal lymph nodes was achieved by sp
iral-CT in 21 of the 28 patients, in 22 of the 28 patients by PET, in 24 pa
tients by CT&PET and in 25 patients by CT+PET.
Conclusions. CT+PET is more accurate than spiral-CT and PET alone in stagin
g mediastinal lymph node involvement in lung cancer patients, with possible
implications for their prognosis and therapy.