Evaluation of a rapid assay for detection of Chlamydia trachomatis infections in outpatient clinics in South Kalimantan, Indonesia

A multicenter cross-sectional survey was conducted comparing a commercially available chlamydial optical immunoassay (OIA) to the chlamydial ligase ch ain reaction (LCR). Endocervical samples from 415 outpatients visiting clin ics from three hospitals in South Kalimantan, Indonesia, were evaluated. Re lative to the LCR, the overall sensitivity and specificity of the OLA were 31.6 and 98.9%, respectively. The sensitivity of the OIA varied among the t hree hospital laboratories, ranging from 20 to 50%, The OIA performance was slightly lower on samples from patients attending dermatovenereology clini cs than on samples from nondermatovenereology clinic patients. The results indicate that the OIA did not perform well compared to LCR.