Sp. Chauhan et al., Accuracy of sonographically estimated fetal weight with and without oligohydramnios - A case-control study, J REPRO MED, 44(11), 1999, pp. 969-973
OBJECTIVE: To determine the accuracy of sonographically estimated fetal wei
ght among women with and without oligohydramnios (amniotic fluid index [AFI
] less than or equal to 5.0 cm) and to ascertain the ability to detect feta
l growth restriction (FGR) (estimated birth weight <10th percentile for ges
tational age [GA]) among patients in two groups.
STUDY DESIGN: Assuming that 50% of sonographic predictions are within 10% o
f the birth weight in the study group, 300 parturients are necessary to sho
w a difference of 15% among controls (alpha=.05, beta=.02). The study group
consisted of parturients with a reliable GA of greater than or equal to 24
, no known anomalies and known AFI of less than or equal to 5.0 cm. The con
trol (1:1) was the next patient with the same GA but AFI between 5.1 and 23
.9 cm. The paired t test was used, and the odds ratio (OX) and 95% confiden
ce interval (CI) were calculated. P < .05 was considered significant.
RESULTS: Among the study and control groups (N = 162 each), maternal demogr
aphics, mean estimate (P = .078) and actual birth weight (P=.091) were simi
lar. Sonographic estimates within 10% of weight were not significantly diff
erent among those with (57%) and without oligohydramnios (59%; OR 0.92; 95%
CI 0.59, 1.44). The frequency of FGR was higher among those with inadequat
e fluid (18%) than controls (9%; OX 2.13; 95% CI 1.10, 4.16). Sensitivity,
positive predictive value and likelihood ratio were higher among those with
oligohydramnios (76%, 78% and 16) than controls (53%, 42% and 7).
CONCLUSION: The accuracy of sonographic estimates of fetal weight is not in
fluenced by whether the parturient has oligohydramnios. Moreover, the accur
acy of identifying FGR is not diminished among those with AFI less than or
equal to 5.0 versus >5.0 cm.