New ring construction strategy in taxane synthesis: stereocontrolled synthesis of taxane CB-ring system

Citation
Cq. Wei et al., New ring construction strategy in taxane synthesis: stereocontrolled synthesis of taxane CB-ring system, J CHEM S P1, (23), 1999, pp. 3531-3536
Citations number
32
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
23
Year of publication
1999
Pages
3531 - 3536
Database
ISI
SICI code
0300-922X(1999):23<3531:NRCSIT>2.0.ZU;2-Q
Abstract
A concise stereocontrolled construction of taxane CB-ring system (C --> CB) is described. The key bottom and top linking of the eight-membered B-ring were realized unprecedentedly by way of successive intermolecular aldol con densation and intramolecular aldol cyclization.