Stereoselective synthesis of 1 'beta-2 ',3 '-dideoxy-2 '-bis(ethoxycarbonyl)methyluridine nucleosides by ring opening of cyclopropanated glycals

Authors
Lim, J Kim, YH
Citation
J. Lim et Yh. Kim, Stereoselective synthesis of 1 'beta-2 ',3 '-dideoxy-2 '-bis(ethoxycarbonyl)methyluridine nucleosides by ring opening of cyclopropanated glycals, J CHEM S P1, (22), 1999, pp. 3239-3241
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
22
Year of publication
1999
Pages
3239 - 3241
Database
ISI
SICI code
0300-922X(1999):22<3239:SSO1''>2.0.ZU;2-5
Abstract
Cyclopropanations of glycals followed by Lewis acid-mediated glycosylations with 5-substituted uracils afforded 1'beta-2',3'-dideoxy-2'-bis(ethoxycarb onyl)methyluridine nucleosides in a highly regiospecific and stereoselectiv e manner in good yields.