MAGNETIC STIMULATION IN THE DIAGNOSIS OF CNS AND PNS DISORDERS

Magnetic stimulation of the cerebral cortex and roots CVI-CVII and LII -LIV was performed in 19 healthy subjects, 45 multiple sclerosis (MS), 21 lateral amyotrophic sclerosis and 24 demyelinizing polyneuropathy patients. M-response of m. Abdueter digiti min (AdV) and m. Tibialis a nt. (TA) was registered. The difference of M-response latent time indu ced by the stimulation, CVI-CVII and LII-LIV determined the time of th e impulse central conduction (ICC) to the corresponding roots. In heal thy subjects ICC-C amounts to 8.28 +/- 1 ms (maximum 10.3 ms), ICC-S i s equal to 14.6 +/- 1.46 ms (maximum 16.8 ms). In patients with the ab ove affections increased ICC was a frequent finding which also occurre d in subclinical pyramidal lesions.