IMMUNOGLOBULIN AGAINST TICK-BORNE ENCEPHA LITIS - THERAPEUTIC EFFICACY, SPECIFIC ACTIVITY, ADMINISTRATION SCHEDULE

A controlled clinical trial included 115 patients with meningeal and f ocal tick-borne encephalitis. 38 of them received nonspecific treatmen t alone, 77 were given adjuvant intramuscular immunoglobulin against t ick-borne encephalitis. The latter are shown to improve much more rapi dly than patients treated only symptomatically. When calculating adequ ate immunglobulin doses, it is necessary to take in consideration not only the amount of the compound, but also the concentration of the spe cific antibodies. The authors propose treatment schemes for patients w ith meningeal and focal tick-borne encephalitis.