Severe skin reactions from interventional fluoroscopy: Case report and review of the literature

Some patients with certain preexisting health conditions may be at elevated risk for unusually intense radiation-induced skin reactions and late tissu e damage from high-dose interventional procedures. The authors present a ca se report of a patient with mixed connective tissue disease and non-insulin -dependent diabetes mellitus who developed an unusual complication after pl acement of a transjugular intrahepatic portosystemic shunt. On the basis of a review of the literature, the following experiences may help identify pa tients at increased risk: previous high-dose procedures, connective tissue disease, diabetes mellitus, and homozygosity for ataxia telangiectasia.