THE INTEGRATION HOST FACTOR-DNA COMPLEX UPSTREAM OF THE EARLY PROMOTER OF BACTERIOPHAGE-MU IS FUNCTIONALLY SYMMETRICAL

Authors
VANULSEN P HILLEBRAND M ZULIANELLO L VANDEPUTTE P GOOSEN N
Citation
P. Vanulsen et al., THE INTEGRATION HOST FACTOR-DNA COMPLEX UPSTREAM OF THE EARLY PROMOTER OF BACTERIOPHAGE-MU IS FUNCTIONALLY SYMMETRICAL, Journal of bacteriology, 179(9), 1997, pp. 3073-3075
Citations number
28
Categorie Soggetti
Microbiology
Journal title
Journal of bacteriology → ACNP
ISSN journal
00219193
Volume
179
Issue
9
Year of publication
1997
Pages
3073 - 3075
Database
ISI
SICI code
0021-9193(1997)179:9<3073:TIHFCU>2.0.ZU;2-3
Abstract
Inversion of the ihf site in the promoter region of the early promoter of bacteriophage Mu did not influence the integration host factor (IH F)-mediated functions. IHF bound to this inverted site could counterac t H-NS-mediated repression, directly activate transcription, and suppo rt lyric growth of bacteriophage Mu. This implies that the IHF heterod imer and its asymmetrical binding site form a functionally symmetrical complex.