Ea. Varanda et al., Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens, TER CAR MUT, 19(6), 1999, pp. 403-413
The antimutagenic effect of ethanolic extract of propolis (EEP) and honeybe
e (Apis mellifera) venom, both collected in the State of Sb Paulo, Brazil,
was assessed by the Salmonella/microsome assay upon direct- and indirect-ac
ting mutagens. EEP had inhibitory effect (in an ascending order) on the mut
agenicity power of daunomycin (TA102), benzo(a)pyrene (TA100), and aflatoxi
n B-1(TA98) and the venom acted against the mutagenicity of 4-nitro-o-pheny
lenediamine (TA98) and daunomycin (TA102). (C) 1999 Wiley-Liss, Inc.