Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens

Authors
Varanda, EA Monti, R Tavares, DC
Citation
Ea. Varanda et al., Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens, TER CAR MUT, 19(6), 1999, pp. 403-413
Citations number
44
Categorie Soggetti
Pharmacology & Toxicology
Journal title
TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS
ISSN journal
02703211 → ACNP
Volume
19
Issue
6
Year of publication
1999
Pages
403 - 413
Database
ISI
SICI code
0270-3211(1999)19:6<403:IEOPAB>2.0.ZU;2-5
Abstract
The antimutagenic effect of ethanolic extract of propolis (EEP) and honeybe e (Apis mellifera) venom, both collected in the State of Sb Paulo, Brazil, was assessed by the Salmonella/microsome assay upon direct- and indirect-ac ting mutagens. EEP had inhibitory effect (in an ascending order) on the mut agenicity power of daunomycin (TA102), benzo(a)pyrene (TA100), and aflatoxi n B-1(TA98) and the venom acted against the mutagenicity of 4-nitro-o-pheny lenediamine (TA98) and daunomycin (TA102). (C) 1999 Wiley-Liss, Inc.