Signaling mechanism of the AT2 angiotensin II receptor: Crosstalk between AT1 and AT2 receptors in cell growth

Authors
Horiuchi, M Lehtonen, JYA Daviet, L
Citation
M. Horiuchi et al., Signaling mechanism of the AT2 angiotensin II receptor: Crosstalk between AT1 and AT2 receptors in cell growth, TRENDS ENDO, 10(10), 1999, pp. 391-396
Citations number
44
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
TRENDS IN ENDOCRINOLOGY AND METABOLISM
ISSN journal
10432760 → ACNP
Volume
10
Issue
10
Year of publication
1999
Pages
391 - 396
Database
ISI
SICI code
1043-2760(199912)10:10<391:SMOTAA>2.0.ZU;2-I
Abstract
The peptide angiotensin (Ang) II exerts a range of actions in the cardiovas cular, renal reproductive and central nervous systems. At least two distinc t Ang II receptor subtypes have been defined and designated as type 1 (AT1) and type 2 (AT2). The function and signaling mechanism of these receptor s ubtypes are quite different, and these receptors exert opposite effects on cell growth.