Vitamin D and hip fracture

Citation
M. Pfeifer et Hw. Minne, Vitamin D and hip fracture, TRENDS ENDO, 10(10), 1999, pp. 417-420
Citations number
37
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
TRENDS IN ENDOCRINOLOGY AND METABOLISM
ISSN journal
10432760 → ACNP
Volume
10
Issue
10
Year of publication
1999
Pages
417 - 420
Database
ISI
SICI code
1043-2760(199912)10:10<417:VDAHF>2.0.ZU;2-5
Abstract
Hip fractures are recognized as a major public health problem worldwide. De mographic changes will lead to enormous increases in the number of hip frac tures and projections indicate that the number of hip fractures occurring w orldwide each year will rise from 1.26 million in 1990 to 4.5 million by 20 50. However, preventive strategies are available. Supplementation with Ca2 and vitamin D restores bone quality through suppression of secondary hyper parathyroidism and decreases the risk of falling through improvement of neu romuscular coordination and body sway. This leads to a reduction of hip fra cture risk of 43% in the vitamin D-insufficient elderly. Treatment with the bisphosphonate alendronate increases bone strength and results in a 51% re duction of hip fracture risk. Hip protectors absorb energy during a fall an d reduce hip fracture risk by 56%. Combining these three procedures could p revent a large proportion of hip fractures in the future.