Primary photosensitization was observed in 3 Appaloosa mares, The skin lesi
ons were diffuse erythema followed by edema and subsequently weeping and fi
nally dry gangrene and ulceration. The severe photosensitivity dermatitis w
as apparently induced by gluten ingestion. Resolution of lesions occurred a
fter withdrawal of the suspected dairy concentrate feed and prevention of e
xposure to sunlight. Neither the ponies nor donkey, which were not fed with
the suspected concentrate, exhibited similar skin lesions;or other clinica
l abnormalities. Gluten metabolites may contain photodynamic agents that ca
use photosensitization in horses.