Tissue reactivity to poliglecaprone 25 in the feline linea alba

Objective-To use poliglecaprone 25 for all ligations and closure in routine feline ovariohysterectomies and evaluate maintenance of tissue approximati on and tissue reaction to the suture. Study Design-Prospective, descriptive study. Animals-Twenty four female cats. Methods-Ovariohysterectomies were performed in all cats. Abdominal incision s were inspected on days 1, 3, 7, 14, and 28 for dehiscence and swelling. A ll cats were euthanatized postoperatively, group 1 on day 7; group 2 on day 14; and group 3 on day 28. The peritoneal cavity was inspected for adhesio ns and all abdominal incisions were collected en bloc. Each linea alba was histologically evaluated and the inflammatory reaction was characterized. Results-Dehiscence did not occur in any of the 2 1 cats. The incisional swe lling on day I was significantly smaller than on day 7, and the swelling on day 14 was significantly smaller than on days 1, 3, and 7 (P < .05). Intra -abdominal adhesions were found in all groups with the greatest number asso ciated with the peritoneum at the incision site. Tissue reactions in group I were pyogranulomatous or fibromononuclear, group 2 were granulomatous or fibromononuclear, and group 3 were pyogranulomatous, granulomatous, fibromo nonuclear or fibrous. Eosinophilic infiltration was seen in 3 of the 8 cats in group 1. Conclusions-Incisional swelling and inflammatory reactions seen with poligl ecaprone 25 were consistent with those anticipated after implantation of su ture in a surgically created wound. Clinical Relevance-Poliglecaprone 25 appears to be an acceptable suture for use in feline ovariohysterectomy. It causes a relatively short-lived infla mmatory response. (C) Copyright 1999 by The American College of Veterinary Surgeons.