IN-VITRO ACTIVITY OF A NEW ECHINOCANDIN, LY303366, COMPARED WITH THOSE OF AMPHOTERICIN-B AND FLUCONAZOLE AGAINST CLINICAL YEAST ISOLATES

Authors
UZUN O KOCAGOZ S CETINKAYA Y ARIKAN S UNAL S
Citation
O. Uzun et al., IN-VITRO ACTIVITY OF A NEW ECHINOCANDIN, LY303366, COMPARED WITH THOSE OF AMPHOTERICIN-B AND FLUCONAZOLE AGAINST CLINICAL YEAST ISOLATES, Antimicrobial agents and chemotherapy, 41(5), 1997, pp. 1156-1157
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
41
Issue
5
Year of publication
1997
Pages
1156 - 1157
Database
ISI
SICI code
0066-4804(1997)41:5<1156:IAOANE>2.0.ZU;2-Z
Abstract
The in vitro activity of LY303366, a new echinocandin derivative, was evaluated with 191 yeast isolates by a broth microdilution method. The MICs at which 50% of the isolates were inhibited were 0.125 mu g/ml f or Candida albicans and C. tropicalis, 0.25 mu g/ml for C. krusei, C. kefyr, and C. glabrata, and 2.0 mu g/ml for C. parapsilosis.