EFFICACIES OF OFLOXACIN, RIFAMPIN, AND CLINDAMYCIN IN TREATMENT OF STAPHYLOCOCCUS-AUREUS ABSCESSES AND CORRELATION WITH RESULTS OF AN IN-VITRO ASSAY OF INTRACELLULAR BACTERIAL KILLING

Authors
BAMBERGER DM HERNDON BL DEW M CHERN RP MITCHELL H SUMMERS LE MARCUS RF KIM SC SUVARNA PR
Citation
Dm. Bamberger et al., EFFICACIES OF OFLOXACIN, RIFAMPIN, AND CLINDAMYCIN IN TREATMENT OF STAPHYLOCOCCUS-AUREUS ABSCESSES AND CORRELATION WITH RESULTS OF AN IN-VITRO ASSAY OF INTRACELLULAR BACTERIAL KILLING, Antimicrobial agents and chemotherapy, 41(5), 1997, pp. 1178-1181
Citations number
23
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
41
Issue
5
Year of publication
1997
Pages
1178 - 1181
Database
ISI
SICI code
0066-4804(1997)41:5<1178:EOORAC>2.0.ZU;2-V
Abstract
We studied the efficacies of ofloxacin, rifampin, and clindamycin in a Staphylococcus aureus abscess model and seven antimicrobial regimens in an intracellular killing assay, Ofloxacin plus rifampin was the mos t effective regimen in the abscess model, and rifampin and ofloxacin w ere the most active regimens in the intracellular killing assay.