Filgrastim treatment of HIV-infected patients improves neutrophil function

Authors
Pitrak, DL
Citation
Dl. Pitrak, Filgrastim treatment of HIV-infected patients improves neutrophil function, AIDS, 13, 1999, pp. S25-S30
Citations number
33
Categorie Soggetti
Immunology
Journal title
AIDS
ISSN journal
02699370 → ACNP
Volume
13
Year of publication
1999
Supplement
2
Pages
S25 - S30
Database
ISI
SICI code
0269-9370(1999)13:<S25:FTOHPI>2.0.ZU;2-S
Abstract
The effect of Filgrastim (recombinant methionyl human granulocyte colony-st imulating factor) treatment on neutrophil function was studied in HIV-infec ted patients. Filgrastim therapy significantly increased oxidative capacity of neutrophils, increased bacterial killing, and reduced accelerated apopt osis of neutrophils observed in this patient population.