Facial metastasis from colorectal carcinoma is extremely rare. Only two cas
es have been reported in the literature. This is the first reported case of
malar metastasis from colon carcinoma. The patient was a 64-year-old, whit
e woman who underwent a low anterior resection for a nearly obstructive car
cinoma at 20 cm. Her chest X-ray revealed lung metastases, Postoperatively
she was treated with fluorouracil and leucovorin. Twenty months later, she
presented with left facial edema, which progressively increased in size. CT
scan and magnetic resonance imaging with gadolinium showed a large soft ti
ssue mass centered about the left anterior zygomatic arch. The platysma mus
cle was displaced laterally, and the masseter muscle was involved. There wa
s extension into the masticator space and bony involvement of the zygomatic
arch. True-cut biopsy of the left cheek revealed metastatic adenocarcinoma
. Histology was similar to that of the primary rectal adenocarcinoma. Metas
tasis to the malar region is extremely rare. It is a grave prognostic sign,
as it is associated with advanced terminal disease. Because of the widespr
ead metastases, only palliative treatment can be provided.