Preoperative starvation in order to prevent pulmonary aspiration is mandato
ry in elective pediatric surgery. Hypoglycemia, thirst and unwellness have
been reported as undesired side effects. The metabolic response towards dec
reasing blood-glucose concentrations in fasting children includes gluconeog
enesis and production of ketone bodys to meet the energetic demand. Accumul
ation of beta-hydroxybutyrate und acetoacetate in blood can lead to ketoaci
dosis. We report a case of a severe intraoperative ketoacidosis in a fourte
en months old child complicating 36 hours of starvation.