Two-dimensional biochemical imaging sensor for spatially resolved glutamate monitoring

A two-dimensional biochemical sensor has been developed for spatially resol ved imaging and sensing with 0.2 mu M glutamate sensitivity and fast respon se. The glutamate sensor was made by covalently immobilizing glutamate dehy drogenase onto hat silica plates. The two-dimensional sensor has the advant age of capturing simultaneous measurements at multiple points and may thus allow better understanding of many biological and chemical processes throug h spatially resolved sensing and imaging. (C) 1999 Elsevier Science B.V. Al l rights reserved.