Efficacy of bisphosphonates in primary neonatal hyperparathyroidism

Authors
Loeuille, GA Cuvellier, JC Thieuleux, M Proye, C
Citation
Ga. Loeuille et al., Efficacy of bisphosphonates in primary neonatal hyperparathyroidism, ANN PEDIAT, 46(9), 1999, pp. 596-600
Citations number
27
Categorie Soggetti
Pediatrics
Journal title
ANNALES DE PEDIATRIE
ISSN journal
00662097 → ACNP
Volume
46
Issue
9
Year of publication
1999
Pages
596 - 600
Database
ISI
SICI code
0066-2097(199911)46:9<596:EOBIPN>2.0.ZU;2-U
Abstract
A typical case of primary neonatal hyperparathyroidism (PNH) is reported. A study of the family found no evidence of familial hypercalcemia with hypoc alciuria (FHH). The relationships between PNH and FHH are discussed, Conven tional medical therapy is only partly effective in reducing the serum calci um levels, which are extremely high initially. Addition of a bisphosphonate and of calcitonin allows to return serum calcium levels to normal before s urgery.