There are numerous methods cited in the literature on the treatment of pain
ful neuroma. Nonsurgical methods range from injections with various materia
ls into the nerve end to desensitization of nerve pain conduction pathways.
Some surgical treatments aim to alter the environment of the amputated ner
ve end by transposing it into muscle or bone, others have designed various
flaps to protect truncated nerve ends from scar tissue, and still others tr
y to "cap" the nerve with silicon, a nerve graft, or epineurium to prevent
nerve regeneration. All of these methods have proved efficient. However, no
ne of these methods work universally. The authors review the common treatme
nts for painful neuromas. In addition, they review the preliminary results
of the extended autologous venous nerve conduit as a novel technique of tre
ating painful neuromas. They also report recent investigations into the pat
hophysiology of injured nerves.