In vitro activities of ketolide HMR3647, macrolides, and other antibioticsagainst Lactobacillus, Leuconostoc, and Pediococcus isolates

Authors
Zarazaga, M Saenz, Y Portillo, A Tenorio, C Ruiz-Larrea, F Del Campo, R Baquero, F Torres, C
Citation
M. Zarazaga et al., In vitro activities of ketolide HMR3647, macrolides, and other antibioticsagainst Lactobacillus, Leuconostoc, and Pediococcus isolates, ANTIM AG CH, 43(12), 1999, pp. 3039-3041
Citations number
32
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
43
Issue
12
Year of publication
1999
Pages
3039 - 3041
Database
ISI
SICI code
0066-4804(199912)43:12<3039:IVAOKH>2.0.ZU;2-1
Abstract
Testing of susceptibility to 13 antibiotics was performed with 90 isolates of Lactobacillus, Leuconostoc, and Pediococcus. MICs at which 90% of the is olates tested were inhibited by HMR3647, erythromycin, and ciprofloxacin we re 0.015, 0.125 and 32 mu g/ml, respectively. The penicillin MIC was greate r than or equal to 16 mu g/ml against 26.2% of the studied Lactobacillus sp . isolates and 50% of Lactobacillus plantarum. HMR3647 showed excellent act ivity against these genera.