Vs. Ocana et al., Characterization of a bacteriocin-like substance produced by a vaginal Lactobacillus salivarius strain, APPL ENVIR, 65(12), 1999, pp. 5631-5635
A novel bacteriocin-like substance produced by vaginal Lactobacillus saliva
rius subsp. salivarius CRL 1328 with activity against Enterococcus faecalis
, Enterococcus faecium, and Neisseria gonorrhoeae was characterized, The hi
ghest level of production of this heat-resistant peptide or protein occurre
d during the late exponential phase. Its mode of action was shown to be bac
tericidal. L. salivarius subsp. salivarius CRL 1328 could be used for the d
esign of a probiotic to prevent urogenital infections.