Host cell signal transduction during Listeria monocytogenes infection

The facultative intracellular bacterial pathogen Listeria monocytogenes inv ades and multiplies in many mammalian cell types. During the interaction wi th its host cells it strongly interferes with and modulates host cell funct ions. In the present review we summarize the current knowledge on the modul ation of signal transduction pathways by secreted listerial products prior to bacterium-cell contact, during uptake, or while L. monocytogenes resides in the different intracellular compartments, (C) 1999 Academic Press.