A questionnaire was sent to senior partners in all general practices in Sco
tland designed to elicit experience of patients with gender dysphoria: a su
bjective experience of incongruity between genital anatomy and gender ident
ity. Responses were received from 73% of practices. The prevalence of gende
r dysphoria among patients aged over 15 years was calculated as 8.18 per 10
0 000, with an approximate sex ratio of 4:1 in favour of male-to-female pat
ients. One-third of gender-dysphoric patients known to practices had regist
ered in the preceding 12 months, suggesting that patients with this conditi
on are increasingly likely to present for medical care.